
The Hidden Gatekeepers: How Ubiquitin-Specific Proteases Shape Breast Cancer’s Pathways
Key Takeaways: Breast cancer is the most common malignancy among women worldwide, associated with complex resistance and survival mechanisms. Ubiquitin-specific proteases (USPs) play a crucial role in regulating cell death pathways, including apoptosis, autophagy, and necroptosis, influencing cancer survival and destruction. USPs